- Characterization of modulators and functional analysis of Kv7 channels and/or proteases
Working with transfection of heteromeric channel constructs; different electrophysiology techniques in oocytes and cells, stem cell derived 2D-cell cultures; high resolution microscopy; 3D modeling protein of individual electrical active cells and cells in a tissue like conformation
Part of Research...
Vollzeitstellen: PHD Jobs
- 100.000 Produkte und Werkzeuge aus den starken Metallen Wolfram und Molybdän: das ist seit über 100 Jahren unsere Mission und unsere Leidenschaft, die 11.000 Mitarbeiter:innen aller Welt teilen. Wir von der Plansee Group haben noch viel vor – und werden mit Ihnen noch besser! Werden Sie Teil unseres Teams! We invite applications for a fully funded PhD position in the field of dataassisted computational modelling of particulate multiscale...
- Generate collagenase-sensitive probes whose cleavage site depends on native triple-helical conformation of collagen
Equip these collagenase-sensitive probes with FRET (Förster resonance energy transfer)- and FLIM (fluorescence life time microscopy)-capable molecular moieties, which enable fluorescence-based real-time monitoring of their cleavage
Determine characteristic features of the probes, such as thermal stability of the triple-helical...
- Processing, quality control and analysis of scRNA-seq, scATAC-seq and spatial transcriptomics datasets
Implementation and adaptation of machine-learning and AI methods for cell type identification, trajectory inference and regulatory network analysis
Integration of multi-omics data (e.g. genomics, transcriptomics, epigenomics) with large-scale cohorts such as UK Biobank
Collaboration with experimental and clinical researchers to define...