- Processing, quality control and analysis of scRNA-seq, scATAC-seq and spatial transcriptomics datasets
Implementation and adaptation of machine-learning and AI methods for cell type identification, trajectory inference and regulatory network analysis
Integration of multi-omics data (e.g. genomics, transcriptomics...
Befristete Anstellungen: PHD Jobs: C++
- The successful candidate will become part of an interdisciplinary and collaborative team committed to translating molecular insights into new precision-oncology strategies for children with cancer.
Design and perform CRISPR-based genetic perturbation screens in patient-derived and engineered cancer models
Analyze...
- Generate collagenase-sensitive probes whose cleavage site depends on native triple-helical conformation of collagen
Equip these collagenase-sensitive probes with FRET (Förster resonance energy transfer)- and FLIM (fluorescence life time microscopy)-capable molecular moieties, which enable fluorescence-based...
- Conduct research on vascular and lymphatic regulation of gonad development using zebrafish as a vertebrate model
Apply and develop methodologies such as in vivo imaging, CRISPR/Cas9-based genome editing, single-cell transcriptomics, and analysis of vascular and lymphatic mutants
Work with human iPSC-derived gonadal...
- We are seeking a highly motivated PhD student to join our interdisciplinary research team to develop a novel biophysical modeling approach based on diffusion-weighted magnetic resonance imaging to comprehensively characterize the tumor microenvironment (TME). Tasks will involve the development of improved...