- Characterization of modulators and functional analysis of Kv7 channels and/or proteases
Working with transfection of heteromeric channel constructs; different electrophysiology techniques in oocytes and cells, stem cell derived 2D-cell cultures; high resolution microscopy; 3D modeling protein of individual electrical active cells and cells in a tissue like conformation
Part of Research...
PHD Stellenangebote
: 6 aktuelle Jobangebote
- We are seeking a highly motivated PhD student to join our interdisciplinary research team to develop a novel biophysical modeling approach based on diffusion-weighted magnetic resonance imaging to comprehensively characterize the tumor microenvironment (TME). Tasks will involve the development of improved biophysical models and corresponding MRI data acquisition protocols to characterize both cellular and vascular properties of the TME. The...
- Conduct research on vascular and lymphatic regulation of gonad development using zebrafish as a vertebrate model
Apply and develop methodologies such as in vivo imaging, CRISPR/Cas9-based genome editing, single-cell transcriptomics, and analysis of vascular and lymphatic mutants
Work with human iPSC-derived gonadal organoids (Optional/depending on project focus)
Analyze, document, and present research findings; contribute to publications and...
- 100.000 Produkte und Werkzeuge aus den starken Metallen Wolfram und Molybdän: das ist seit über 100 Jahren unsere Mission und unsere Leidenschaft, die 11.000 Mitarbeiter:innen aller Welt teilen. Wir von der Plansee Group haben noch viel vor – und werden mit Ihnen noch besser! Werden Sie Teil unseres Teams! We invite applications for a fully funded PhD position in the field of dataassisted computational modelling of particulate multiscale...
- Generate collagenase-sensitive probes whose cleavage site depends on native triple-helical conformation of collagen
Equip these collagenase-sensitive probes with FRET (Förster resonance energy transfer)- and FLIM (fluorescence life time microscopy)-capable molecular moieties, which enable fluorescence-based real-time monitoring of their cleavage
Determine characteristic features of the probes, such as thermal stability of the triple-helical...
- The successful candidate will become part of an interdisciplinary and collaborative team committed to translating molecular insights into new precision-oncology strategies for children with cancer.
Design and perform CRISPR-based genetic perturbation screens in patient-derived and engineered cancer models
Analyze and interpret epigenetic, transcriptomic, and proteomic datasets using state-of-the-art statistical and computational...