- Characterization of modulators and functional analysis of Kv7 channels and/or proteases
Working with transfection of heteromeric channel constructs; different electrophysiology techniques in oocytes and cells, stem cell derived 2D-cell cultures; high resolution microscopy; 3D modeling protein of individual electrical active cells and cells in a tissue like conformation
Part of Research...
Student Stellenangebote von Universitätsklinikum Münster
: 4 aktuelle Jobangebote
- We are seeking a highly motivated PhD student to join our interdisciplinary research team to develop a novel biophysical modeling approach based on diffusion-weighted magnetic resonance imaging to comprehensively characterize the tumor microenvironment (TME). Tasks will involve the development of improved biophysical models and corresponding MRI data acquisition protocols to characterize both cellular and vascular properties of the TME. The...
- Conduct research on vascular and lymphatic regulation of gonad development using zebrafish as a vertebrate model
Apply and develop methodologies such as in vivo imaging, CRISPR/Cas9-based genome editing, single-cell transcriptomics, and analysis of vascular and lymphatic mutants
Work with human iPSC-derived gonadal organoids (Optional/depending on project focus)
Analyze, document, and present research findings; contribute to publications and...
- Generate collagenase-sensitive probes whose cleavage site depends on native triple-helical conformation of collagen
Equip these collagenase-sensitive probes with FRET (Förster resonance energy transfer)- and FLIM (fluorescence life time microscopy)-capable molecular moieties, which enable fluorescence-based real-time monitoring of their cleavage
Determine characteristic features of the probes, such as thermal stability of the triple-helical...